Research
Open problems
Questions we have not solved. If you are working on one, we would like to hear from you.
Life sciences
Pair-level interaction labels
Most herb–drug records describe the drug studied, not the outcome for a pair. How can pharmacologists produce pair-level labels quickly and consistently enough to train on?
Life sciences
Interactions beyond enzymes
Our mechanism model covers enzyme-mediated interactions. How should transporter and pharmacodynamic interactions be modelled with the same traceability?
Life sciences
Classical and modern sources together
How should a model weigh a classical text against a modern assay when they disagree, and show that disagreement to a reader?
Realtime video
Long-clip drift
Which consistency metric catches slow drift over minutes without penalising intended change?
Media intelligence
Tone across languages
How do you calibrate a tone label so it means the same thing in Hindi, Tamil and English coverage?
Software from intent
Tests from intent
Can acceptance tests be written from a plain-language request reliably enough that passing them means the app does what was meant?
Working on one of these?
Subject: Open problem